Nicholas P J Day Selected Research

piperaquine

10/2021	Arterolane-piperaquine-mefloquine versus arterolane-piperaquine and artemether-lumefantrine in the treatment of uncomplicated Plasmodium falciparum malaria in Kenyan children: a single-centre, open-label, randomised, non-inferiority trial.
1/2020	The use of ultrasensitive quantitative-PCR to assess the impact of primaquine on asymptomatic relapse of Plasmodium vivax infections: a randomized, controlled trial in Lao PDR.
1/2020	Triple artemisinin-based combination therapies versus artemisinin-based combination therapies for uncomplicated Plasmodium falciparum malaria: a multicentre, open-label, randomised clinical trial.
1/2020	Combining antimalarial drugs and vaccine for malaria elimination campaigns: a randomized safety and immunogenicity trial of RTS,S/AS01 administered with dihydroartemisinin, piperaquine, and primaquine in healthy Thai adult volunteers.
1/2020	Pooled Multicenter Analysis of Cardiovascular Safety and Population Pharmacokinetic Properties of Piperaquine in African Patients with Uncomplicated Falciparum Malaria.
1/2019	The impact of targeted malaria elimination with mass drug administrations on falciparum malaria in Southeast Asia: A cluster randomised trial.
11/2018	The dynamic of asymptomatic Plasmodium falciparum infections following mass drug administrations with dihydroarteminisin-piperaquine plus a single low dose of primaquine in Savannakhet Province, Laos.
1/2018	A Controlled Trial of Mass Drug Administration to Interrupt Transmission of Multidrug-Resistant Falciparum Malaria in Cambodian Villages.
12/2017	Population pharmacokinetics and electrocardiographic effects of dihydroartemisinin-piperaquine in healthy volunteers.
11/2017	The prevalence, incidence and prevention of Plasmodium falciparum infections in forest rangers in Bu Gia Map National Park, Binh Phuoc province, Vietnam: a pilot study.

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Nicholas P J Day Research Topics

Disease

101	Malaria 03/2024 - 09/2003
74	Falciparum Malaria (Plasmodium falciparum Malaria) 10/2023 - 08/2004
65	Infections 03/2024 - 03/2003
45	Melioidosis 03/2024 - 08/2004
35	Scrub Typhus (Typhus, Scrub) 01/2024 - 07/2007
16	Fever (Fevers) 01/2024 - 03/2004
15	Vivax Malaria 02/2024 - 04/2007
10	Glucosephosphate Dehydrogenase Deficiency 05/2024 - 08/2013
10	Coma (Comas) 01/2019 - 01/2009
10	Dengue (Dengue Fever) 01/2019 - 04/2006
8	Hemolysis 05/2024 - 01/2014
8	Sepsis (Septicemia) 01/2021 - 08/2007
8	Typhoid Fever (Typhoid) 01/2021 - 03/2004
7	COVID-19 04/2024 - 01/2022
7	Bacteremia 11/2021 - 03/2005
7	Parasitemia 12/2020 - 04/2007
6	Communicable Diseases (Infectious Diseases) 02/2024 - 10/2009
6	Human Influenza (Influenza) 01/2024 - 09/2006
6	Acidosis 01/2019 - 08/2004
5	Leptospirosis 10/2020 - 09/2007
5	Endemic Flea-Borne Typhus (Typhus, Endemic Flea Borne) 01/2020 - 07/2007
5	Cerebral Malaria 01/2017 - 07/2009
5	Reinfection 11/2012 - 04/2007
4	Tetanus 03/2023 - 11/2004
4	Bacterial Infections (Bacterial Infection) 07/2020 - 01/2011
4	Hypoxia (Hypoxemia) 03/2019 - 11/2009
4	Body Weight (Weight, Body) 01/2017 - 07/2009
3	Vomiting 01/2022 - 01/2020
3	Lymphadenopathy 01/2018 - 01/2013
3	Acute malaria 01/2015 - 01/2014
3	Epidemic Louse-Borne Typhus (Typhus) 03/2012 - 02/2008
2	Pneumonia (Pneumonitis) 10/2023 - 09/2023
2	Thrombocytopenia (Thrombopenia) 09/2020 - 01/2017
2	Drug-Related Side Effects and Adverse Reactions 01/2020 - 10/2005
2	Lactic Acidosis 03/2019 - 04/2013

Drug/Important Bio-Agent (IBA)

35	Antimalarials (Antimalarial Agents)IBA 12/2022 - 04/2007
30	artemisinin (artemisinine)IBA 01/2022 - 11/2008
29	Immunoglobulin M (IgM)IBA 12/2020 - 08/2004
26	Anti-Bacterial Agents (Antibiotics)IBA 02/2024 - 11/2002
22	Primaquine FDA Link 05/2024 - 06/2006
22	ArtesunateIBA 12/2020 - 06/2006
21	AntibodiesIBA 11/2021 - 09/2005
17	AntigensIBA 11/2021 - 08/2005
17	piperaquineIBA 10/2021 - 04/2010
17	Immunoglobulin G (IgG)IBA 01/2021 - 03/2003
15	EnzymesIBA 11/2021 - 08/2004
14	artenimol (dihydroartemisinin)IBA 01/2020 - 04/2010
13	VaccinesIBA 09/2023 - 11/2004
13	Quinine (Quinson)FDA Link 01/2017 - 06/2006
11	Proteins (Proteins, Gene)FDA Link 01/2023 - 03/2003
11	ImmunosorbentsIBA 11/2021 - 08/2004
10	Biomarkers (Surrogate Marker)IBA 03/2024 - 01/2012
9	DNA (Deoxyribonucleic Acid)IBA 03/2024 - 07/2010
8	Lumefantrine Drug Combination Artemether (Coartem)FDA Link 01/2022 - 09/2008
8	Lactic Acid (Lactate)FDA LinkGeneric 03/2019 - 08/2004
7	Antiviral Agents (Antivirals)IBA 04/2024 - 01/2016
7	Mefloquine (Lariam)FDA LinkGeneric 10/2021 - 04/2009
7	AcidsIBA 01/2019 - 08/2004
6	Doxycycline (Periostat)FDA LinkGeneric 06/2023 - 10/2005
6	Chloroquine (Aralen)FDA LinkGeneric 01/2019 - 04/2010
5	Glucosephosphate Dehydrogenase (Glucose 6 Phosphate Dehydrogenase)IBA 11/2017 - 04/2010
5	Lumefantrine FDA Link 10/2015 - 09/2008
4	Azithromycin (Zithromax)FDA LinkGeneric 06/2023 - 09/2007
4	Ceftazidime (Fortum)FDA LinkGeneric 01/2023 - 08/2007
4	Sulfamethoxazole Drug Combination Trimethoprim (Co-Trimoxazole)FDA LinkGeneric 01/2023 - 10/2005
4	CytokinesIBA 01/2022 - 01/2013
4	Hemoglobins (Hemoglobin)IBA 01/2020 - 01/2017
4	Oseltamivir (Tamiflu)FDA Link 01/2016 - 09/2006
3	Tryptophan (L-Tryptophan)FDA Link 10/2023 - 09/2003
3	Conjugate VaccinesIBA 09/2023 - 11/2015
3	Ivermectin (Mectizan)FDA Link 01/2023 - 01/2020
3	Amodiaquine (Camoquin)FDA Link 01/2022 - 11/2012
3	Polysaccharides (Glycans)IBA 11/2021 - 09/2015
3	C-Reactive ProteinIBA 07/2020 - 11/2015
3	8-aminoquinolineIBA 01/2020 - 03/2016
3	Chloramphenicol (Chloromycetin)FDA Link 01/2019 - 10/2005
3	CreatinineIBA 03/2018 - 01/2017
3	16S Ribosomal RNAIBA 08/2012 - 11/2007
2	tafenoquineIBA 02/2024 - 12/2022
2	Transaminases (Aminotransferases)IBA 02/2024 - 02/2015
2	Oxidoreductases (Dehydrogenase)IBA 02/2024 - 10/2023
2	KynurenineIBA 10/2023 - 09/2003
2	AntitoxinsIBA 03/2023 - 12/2004
2	Amoxicillin-Potassium Clavulanate Combination (Co-amoxiclav)FDA Link 01/2023 - 11/2011
2	Meropenem (Merrem)FDA LinkGeneric 01/2023 - 06/2015
2	Hemolysin Proteins (Hemolysins)IBA 11/2021 - 09/2019
2	Ofloxacin (Ofloxacine)FDA LinkGeneric 01/2021 - 03/2005
2	von Willebrand FactorIBA 09/2020 - 01/2017
2	pyrimethamine drug combination fanasil (Fansidar)FDA Link 03/2020 - 02/2016
2	Folic Acid AntagonistsIBA 03/2020 - 09/2016
2	Drinking WaterIBA 01/2020 - 02/2014
2	Immunoglobulin A (IgA)IBA 09/2019 - 12/2015
2	Amino Acids FDA Link 01/2019 - 11/2018

Therapy/Procedure

25	Therapeutics 09/2023 - 11/2002
16	Mass Drug Administration 11/2021 - 01/2017
7	Critical Care (Surgical Intensive Care) 01/2021 - 11/2004
4	Insecticide-Treated Bednets 11/2018 - 09/2014
2	Artificial Respiration (Mechanical Ventilation) 03/2023 - 01/2018
2	Retreatment 01/2022 - 11/2014
2	Resuscitation 01/2020 - 04/2013